Michael Smith





Michael Smith CC, OBC, FRS (April 26, 1932 – October 4, 2000) was a British-born Canadian biochemist and businessman. He was the winner of the 1993 Nobel Prize in Chemistry (shared with Kary Mullis ) for his work in developing site-directed mutagenesis. Following graduation with a PhD in 1956 from the University of Manchester, he undertook post-doctoral studies with Dr. Har Gobind Khorana (himself a Nobel Prize winner) at the British Columbia Research Council in Vancouver, Canada. Subsequently, Smith worked at the Fisheries Research Board of Canada Laboratory in Vancouver before being appointed a professor of biochemistry in the UBC Faculty of Medicine in 1966.